Semax

Clinical Trials

Cognitive Enhancement

A synthetic ACTH analog that enhances cognitive function, provides neuroprotection, and supports brain recovery from injury.

Administration

Intranasal spray

Dosage Range

200-600 mcg daily

Mechanism of Action

Semax increases BDNF expression, modulates dopamine and serotonin systems, enhances cerebral blood flow, and activates neuroprotective pathways including the MAPK/ERK signaling cascade.

Clinical Benefits

Enhanced memory and learning

Neuroprotection after stroke/TBI

Improved attention and focus

Reduced cognitive decline

Anti-inflammatory brain effects

Clinical Evidence

Approved in Russia for stroke recovery and cognitive disorders. Studies show improved cognitive outcomes in stroke patients and enhanced memory in healthy volunteers.

Side Effects

Nasal irritation

Mild headache

Insomnia at high doses

Contraindications

Acute psychosis

Pregnancy

Seizure disorders (caution)

Related Peptides in Cognitive Enhancement

Selank

A synthetic peptide analog of tuftsin with anxiolytic and nootropic properties that enhances cognitive function without sedation.

Dihexa

An angiotensin IV analog with extraordinary potency for cognitive enhancement, being 10 million times more potent than BDNF at promoting neuronal connections.

Medical Disclaimer: This information is for educational purposes only and does not constitute medical advice. Peptide therapy should only be administered under the supervision of a qualified healthcare provider. Always consult your physician before starting any new treatment protocol.